Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 2/20 | 0.44 |
| ▸ | HTR1B | P28222 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954396 | 0.93 | HTR1D (0.50) | HTR1DHTR1BHTR1ASLC6A4 | |
| SCHEMBL6947219 | 0.91 | HTR1A (0.52) | HTR1AHTR2ACCR3SLC6A4 | |
| SCHEMBL6955648 | 0.86 | HTR2A (0.48) | CARM1PRMT6HTR1AHTR2ACCR3 | |
| SCHEMBL6956030 | 0.85 | HTR1A (0.50) | CARM1PRMT6HTR1DHTR1BHTR1A | |
| SCHEMBL6958541 | 0.85 | SLC6A4 (0.49) | CARM1PRMT6HTR1DHTR1BHTR1A | |
| SCHEMBL6950516 | 0.84 | HTR1A (0.56) | CARM1PRMT6HTR1DHTR1BHTR1A | |
| SCHEMBL6954556 | 0.84 | HTR1A (0.60) | HTR1BHTR1AHTR2ASLC6A4 | |
| SCHEMBL6958270 | 0.83 | TACR1 (0.51) | MEN1KMT2ABCHE | |
| SCHEMBL7879009 | 0.83 | HTR1A (0.55) | CARM1PRMT6HTR1AHTR2ACCR3 | |
| SCHEMBL6953432 | 0.82 | SLC6A4 (0.52) | HTR1AHTR2ACCR3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993458-B1 | 3-BENZYLPIPERIDINE | MERCK PATENT GMBH (DE) | 2003-04-09 | — | — | EP | disclosed |
| US-6333339-B1 | CENTRAL SYSTEM DISORDERS, SCHIZOPHRENIA AND COGNITION ACTIVATORS | MERCK PATENT GELLSCHAFT MIT BESCHRANKTER (DE) | 2001-12-25 | — | — | US | disclosed |
| EP-0993458-A1 | 3-BENZYLPIPERIDINE | MERCK PATENT GmbH (DE) | 2000-04-19 | — | — | EP | disclosed |
| WO-1998057953-A1 | 3-BENZYLPIPERIDINE | MERCK PATENT GMBH (DE) | 1998-12-23 | — | — | WO | disclosed |