Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.36 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.36 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971033 | 0.87 | NR3C1 (0.42) | NR3C1MEP1AMEP1BALKBH1PDK1 | |
| SCHEMBL6972367 | 0.83 | ALKBH1 (0.42) | PTGESCHRM2CHRM1CHRM3MEP1A | |
| SCHEMBL6963537 | 0.82 | PTGES (0.38) | NR3C1PTGESCHRM2CHRM1CHRM3 | |
| SCHEMBL6955000 | 0.80 | PTGES (0.38) | NR3C1PTGESCHRM2CHRM1CHRM3 | |
| SCHEMBL15362537 | 0.79 | HTT (0.41) | MCL1HTR2CSLC6A4CACNA2D1 | |
| SCHEMBL6955361 | 0.79 | PTGES (0.37) | PTGESCHRM2CHRM1CHRM3MEP1A | |
| SCHEMBL1010216 | 0.73 | MEP1A (0.50) | PTGESCHRM2CHRM1CHRM3MEP1A | |
| SCHEMBL320434 | 0.72 | MEP1A (0.49) | PTGESCHRM2CHRM1CHRM3MEP1A | |
| SCHEMBL6964182 | 0.70 | MEP1A (0.38) | PTGESCHRM2CHRM1CHRM3MEP1A | |
| SCHEMBL1010217 | 0.70 | MEP1A (0.47) | PTGESCHRM2CHRM1CHRM3MEP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |