Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.37 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 2/20 | 0.37 |
| ▸ | FNTB | P49356 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966037 | 0.86 | ALKBH1 (0.43) | ALKBH1CHRM2CHRM1CHRM3MEP1A | |
| SCHEMBL6960286 | 0.83 | NR3C1 (0.38) | ALKBH1CHRM2CHRM1CHRM3PTGES | |
| SCHEMBL6955000 | 0.81 | PTGES (0.38) | ALKBH1CHRM2CHRM1CHRM3PTGES | |
| SCHEMBL6963537 | 0.81 | PTGES (0.38) | ALKBH1CHRM2CHRM1CHRM3PTGES | |
| SCHEMBL31456982 | 0.81 | ITGB1 (0.41) | CHRM2CHRM1CHRM3MCL1MEN1 | |
| SCHEMBL6955361 | 0.80 | PTGES (0.37) | ALKBH1CHRM2CHRM1CHRM3PTGES | |
| SCHEMBL1010216 | 0.76 | MEP1A (0.50) | CHRM2CHRM1CHRM3PTGESMEP1A | |
| SCHEMBL24467961 | 0.73 | GPR119 (0.37) | ALKBH1FNTAFNTB | |
| SCHEMBL29741623 | 0.73 | KCNJ1 (0.38) | ALKBH1FNTAFNTB | |
| SCHEMBL320434 | 0.73 | MEP1A (0.49) | CHRM2CHRM1CHRM3PTGESMEP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |