Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 3/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6961354 | 0.86 | CHRNA7 (0.37) | MAPTALDH1A1HSD17B10LMNATSHR | |
| SCHEMBL6961535 | 0.85 | KIT (0.47) | MAPTALDH1A1HSD17B10KDM4ELMNA | |
| SCHEMBL6956633 | 0.83 | MAPT (0.44) | MAPTALDH1A1HSD17B10KDM4ELMNA | |
| SCHEMBL6959773 | 0.81 | KIT (0.38) | MAPTALDH1A1HSD17B10KDM4ELMNA | |
| SCHEMBL6954193 | 0.81 | ALDH1A1 (0.44) | MAPTALDH1A1HSD17B10KDM4ELMNA | |
| SCHEMBL6966890 | 0.81 | KIT (0.47) | MAPTALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL6959299 | 0.80 | MEN1 (0.42) | MAPTLMNAHPGDMAP4K1MEN1 | |
| SCHEMBL6966648 | 0.79 | TP53 (0.41) | MAPTALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL6956780 | 0.77 | MAP4K1 (0.42) | MAPTALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL6955336 | 0.77 | POLB (0.42) | MAPTALDH1A1HSD17B10KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955293-B1 | UREA DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-19 | — | — | EP | claimed |