Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 4/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959537 | 0.87 | VNN1 (0.48) | VNN1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6959349 | 0.86 | VNN1 (0.47) | VNN1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6959326 | 0.76 | VNN1 (0.51) | VNN1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL13688135 | 0.74 | HPGD (0.43) | MAPK14LMNAMAPTCA12CA1 | |
| SCHEMBL6972135 | 0.73 | MEN1 (0.47) | VNN1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6969995 | 0.72 | ACP1 (0.45) | VNN1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6966121 | 0.71 | MEP1A (0.40) | VNN1MAPK14RAB9AMEN1KMT2A | |
| SCHEMBL25781912 | 0.70 | VNN1 (0.50) | VNN1MAOASMN1; SMN2 | |
| SCHEMBL24427767 | 0.69 | SCN8A (0.53) | VNN1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6955432 | 0.69 | MAPT (0.46) | VNN1ACP1METKCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |