Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 3/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.44 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969995 | 0.78 | ACP1 (0.45) | VNN1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6959537 | 0.77 | VNN1 (0.48) | VNN1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6959349 | 0.76 | VNN1 (0.47) | VNN1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6960930 | 0.76 | VNN1 (0.47) | VNN1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6691560 | 0.76 | NOS1 (0.58) | VNN1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL1680823 | 0.74 | LMNA (0.57) | VNN1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL2214866 | 0.72 | GAA (0.53) | GRM5TSHR | |
| SCHEMBL6972135 | 0.72 | MEN1 (0.47) | VNN1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6966037 | 0.72 | ALKBH1 (0.43) | VNN1GRM5ALDH1A1HSD17B10ALKBH1 | |
| SCHEMBL19902102 | 0.71 | GRM5 (0.70) | GRM5GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |