Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.45 |
| ▸ | VNN1 | O95497 | 3/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.41 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960353 | 0.78 | ALDH1A1 (0.41) | ACP1VNN1PDE2ACYP1A2CYP2C19 | |
| SCHEMBL6959326 | 0.78 | VNN1 (0.51) | VNN1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6972135 | 0.78 | MEN1 (0.47) | ACP1VNN1GABRG2GABRB3GABRA5 | |
| SCHEMBL6959349 | 0.77 | VNN1 (0.47) | ACP1VNN1GABRG2GABRB3GABRA5 | |
| SCHEMBL24427767 | 0.74 | SCN8A (0.53) | ACP1VNN1GABRG2GABRB3GABRA5 | |
| SCHEMBL6959537 | 0.73 | VNN1 (0.48) | ACP1VNN1GABRG2GABRB3GABRA5 | |
| SCHEMBL6960930 | 0.72 | VNN1 (0.47) | ACP1VNN1GABRG2GABRB3GABRA5 | |
| SCHEMBL6971033 | 0.72 | NR3C1 (0.42) | DRD2DRD4DRD3ALDH1A1HSD17B10 | |
| SCHEMBL26847567 | 0.70 | NOTUM (0.49) | DRD2DRD3ALDH1A1TSHRKDM4E | |
| SCHEMBL9051881 | 0.69 | LMNA (0.46) | DRD2DRD4DRD3CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |