Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 2/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697433 | 0.88 | NPC1 (0.44) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL697587 | 0.86 | KMT2A (0.42) | NPC1RAB9AKMT2ATSHRBRAF | |
| SCHEMBL703290 | 0.82 | NPC1 (0.44) | NPC1RAB9AMAOAMAOBALDH1A1 | |
| SCHEMBL27845585 | 0.79 | KMT2A (0.37) | NPC1RAB9AKMT2ABRAFALDH1A1 | |
| SCHEMBL697991 | 0.79 | CYP1A2 (0.41) | NPC1RAB9AKMT2ABRAFTAS1R3 | |
| SCHEMBL712135 | 0.78 | NPC1 (0.65) | NPC1RAB9AKMT2ATSHRBRAF | |
| SCHEMBL702086 | 0.77 | KMT2A (0.46) | NPC1RAB9AKMT2ABRAFALDH1A1 | |
| SCHEMBL696226 | 0.76 | KMT2A (0.41) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL1573195 | 0.76 | NPC1 (0.46) | NPC1RAB9AKMT2ANISCHSMN1; SMN2 | |
| SCHEMBL696628 | 0.74 | NPC1 (0.47) | NPC1RAB9AKMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |