Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 5/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970693 | 0.89 | CCR1 (0.41) | HRH1ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL6960366 | 0.86 | HRH1 (0.44) | HRH1ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL6973725 | 0.86 | HRH1 (0.47) | HRH1ADRA1DADRA1AADRA1BHTR1A | |
| Hydrochloric Acid SCHEMBL6960538 | 0.85 | HRH1 (0.43) | HRH1ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL6972127 | 0.81 | OPRK1 (0.43) | HRH1ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL6960765 | 0.81 | HRH1 (0.42) | HRH1ADRA1DADRA1AADRA1BHTR1A | |
| SCHEMBL6964674 | 0.80 | DRD2 (0.48) | HTR1ADRD2HTR7 | |
| SCHEMBL7473583 | 0.76 | SIGMAR1 (0.43) | HRH1SIGMAR1LMNAPMP22PPARG | |
| SCHEMBL6971128 | 0.75 | CCR1 (0.44) | HRH1ADRA1DADRA1AADRA1BHTR1A | |
| Hydrochloric Acid SCHEMBL6969045 | 0.74 | CCR1 (0.43) | HRH1ADRA1DADRA1AADRA1BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934312-B1 | 1,4-DISUBSTITUTED PIPERAZINES | NOVO NORDISK AS (DK) | 2003-03-19 | — | — | EP | claimed |