Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3103834 | 0.82 | STAT3 (0.48) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL30844048 | 0.81 | MAPT (0.44) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL20535502 | 0.79 | PKM (0.47) | — | |
| SCHEMBL6954162 | 0.78 | STAT3 (0.39) | ALDH1A1POLBTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL6994087 | 0.78 | LMNA (0.53) | ALDH1A1POLBMAPTTSHRKMT2A | |
| SCHEMBL26655207 | 0.77 | ALDH1A1 (0.47) | ALDH1A1POLBMAPTGAAKMT2A | |
| SCHEMBL2352786 | 0.76 | PTGS1 (0.49) | ALDH1A1POLBMAPTGAAKMT2A | |
| SCHEMBL2881816 | 0.76 | LMNA (0.43) | ALDH1A1POLBMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL26655501 | 0.75 | MAPT (0.45) | ALDH1A1POLBMAPTGAAKMT2A | |
| SCHEMBL31363722 | 0.74 | MMP1 (0.52) | MMP1MMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562808-B1 | Calcium channel antagonists effective in treating intestinal diseases caused by abnormal acceleration of the contraction of intestinal tracts such as irritable bowel syndrome, without significant cardiac effects | AJINOMOTO CO., INC. (JP) | 2003-05-13 | — | — | US | disclosed |
| EP-1020466-B1 | 5,11-DIHYDRODIBENZ[b,e][1,4]OXAZEPINE DERIVATIVES AND MEDICINAL COMPOSITION CONTAINING THE SAME | AJINOMOTO KK (JP) | 2003-02-19 | — | — | EP | disclosed |
| EP-1020466-A1 | 5,11-DIHYDRODIBENZ[b,e][1,4]OXAZEPINE DERIVATIVES AND MEDICINAL COMPOSITION CONTAINING THE SAME | Ajinomoto Co., Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |