Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960682 | 0.81 | MAPT (0.53) | MAPTALDH1A1GAAKMT2AALOX12 | |
| SCHEMBL1419116 | 0.80 | EPHX1 (0.43) | MAPTALDH1A1GAAKMT2AKDM4E | |
| SCHEMBL7941329 | 0.79 | ALDH1A1 (0.53) | MAPTALDH1A1GAAKMT2AKDM4E | |
| SCHEMBL1275764 | 0.78 | KMT2A (0.72) | MAPTALDH1A1GAAKMT2AKDM4E | |
| SCHEMBL6973539 | 0.77 | TAS2R38 (0.57) | MAPTALDH1A1GAAKMT2AKDM4E | |
| SCHEMBL15675434 | 0.73 | ALDH1A1 (0.68) | MAPTALDH1A1GAAKMT2AKDM4E | |
| SCHEMBL359542 | 0.72 | GAA (0.54) | MAPTALDH1A1GAAKMT2ALMNA | |
| SCHEMBL6967633 | 0.72 | POLB (0.42) | MAPTALDH1A1GAAKMT2AKDM4E | |
| SCHEMBL468076 | 0.72 | — | — | |
| SCHEMBL7102655 | 0.72 | MAOB (0.53) | MAPTALDH1A1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |