Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15484146 | 0.78 | IDO1 (0.75) | MAOBALDH1A1IDO1MAPTNPSR1 | |
| SCHEMBL6960682 | 0.76 | MAPT (0.53) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL7098462 | 0.74 | MAOB (0.61) | MAOBALDH1A1IDO1MAPTNPSR1 | |
| SCHEMBL6944649 | 0.73 | MAOB (0.48) | MAOBALDH1A1IDO1MAPTNPSR1 | |
| SCHEMBL6965156 | 0.72 | MAPT (0.48) | ALDH1A1MAPTKMT2AGAA | |
| SCHEMBL6973539 | 0.72 | TAS2R38 (0.57) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL29481122 | 0.71 | IDO1 (0.79) | MAOBALDH1A1IDO1MAPTMEN1 | |
| SCHEMBL26991 | 0.71 | IDO1 (0.79) | MAOBALDH1A1IDO1MAPTMEN1 | |
| SCHEMBL6815632 | 0.69 | MAOB (0.69) | MAOBALDH1A1IDO1MAPTNPSR1 | |
| Loflucarban SCHEMBL149841 | 0.69 | MAOB (1.00) | MAOBALDH1A1IDO1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339668-A2 | BISUBSTITUTED CARBOCYCLIC CYCLOPHILIN BINDING COMPOUNDS AND THEIRUS | GUILFORD PHARMACEUTICALS INC. (US) | 2003-09-03 | — | — | EP | claimed |
| WO-2002044126-A2 | BISUBSTITUTED CARBOCYCLIC CYCLOPHILIN BINDING COMPOUNDS AND THEIRUS | GUILFORD PHARMACEUTICALS INC. (US) | 2002-06-06 | — | — | WO | claimed |