Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R38 | P59533 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 5/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960682 | 0.81 | MAPT (0.53) | TAS2R38HSD17B10ALDH1A1CYP3A4GAA | |
| SCHEMBL50031 | 0.80 | HSD17B10 (0.57) | HSD17B10ALDH1A1TSHRCYP3A4GAA | |
| SCHEMBL6965156 | 0.77 | MAPT (0.48) | ALDH1A1GAAMAPTKDM4EKMT2A | |
| SCHEMBL3911427 | 0.74 | TDP1 (0.54) | HSD17B10ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL6990986 | 0.74 | NPC1 (0.44) | HSD17B10ALDH1A1TP53TSHRCYP3A4 | |
| SCHEMBL6966858 | 0.74 | TAS2R38 (0.60) | TAS2R38HSD17B10ALDH1A1TP53TYR | |
| SCHEMBL2531539 | 0.73 | EPHX2 (0.41) | HSD17B10TP53TSHRGAAMAPT | |
| SCHEMBL340780 | 0.73 | TAS2R38 (1.00) | TAS2R38HSD17B10ALDH1A1TP53TYR | |
| SCHEMBL359677 | 0.73 | SMN1; SMN2 (0.48) | ALDH1A1CYP3A4GAAMAPTKDM4E | |
| SCHEMBL746119 | 0.73 | ALDH1A1 (0.47) | HSD17B10ALDH1A1TP53TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |