Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 2/20 | 0.41 |
| ▸ | MAX | P61244 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964781 | 0.87 | L3MBTL1 (0.46) | MGLLBLML3MBTL1ALDH1A1MAPT | |
| SCHEMBL6969398 | 0.81 | ALDH1A1 (0.42) | MGLLALDH1A1MAPTNPSR1MEN1 | |
| SCHEMBL6955643 | 0.81 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL6955924 | 0.80 | LMNA (0.47) | MGLLALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6964263 | 0.78 | ALDH1A1 (0.42) | MGLLBLML3MBTL1ALDH1A1MAPT | |
| SCHEMBL6969301 | 0.77 | BRD4 (0.54) | ABCB1MYCMAXL3MBTL1ALDH1A1 | |
| SCHEMBL9414290 | 0.77 | ABCB1 (0.44) | ABCB1MYCMAXHSD17B10MGLL | |
| SCHEMBL6959345 | 0.77 | PDE4A (0.45) | ALDH1A1MAPTNPSR1MEN1KMT2A | |
| SCHEMBL6962161 | 0.77 | LMNA (0.49) | MGLLBLML3MBTL1ALDH1A1MAPT | |
| SCHEMBL6964164 | 0.76 | NPSR1 (0.46) | HSD17B10ALDH1A1MAPTNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |