Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | VDR | P11473 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | MAX | P61244 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955057 | 0.86 | BRD4 (0.57) | BRD4MAPTALDH1A1HTTL3MBTL1 | |
| SCHEMBL6970210 | 0.81 | BRD4 (0.59) | BRD4MAPTALDH1A1HTTL3MBTL1 | |
| SCHEMBL6965183 | 0.77 | ABCB1 (0.43) | ABCB1MAPTALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL6971322 | 0.76 | ALDH1A1 (0.60) | BRD4MAPTALDH1A1HTTL3MBTL1 | |
| SCHEMBL6964190 | 0.76 | BRD4 (0.60) | BRD4ALDH1A1HTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL6966939 | 0.75 | TUBB4A (0.46) | BRD4MAPTALDH1A1HTTPOLB | |
| SCHEMBL6954979 | 0.75 | TUBB4A (0.45) | BRD4MAPTALDH1A1POLBCRBN | |
| SCHEMBL4909516 | 0.74 | ABCB1 (0.49) | ABCB1MAPTSMN1; SMN2MYCMAX | |
| SCHEMBL30082870 | 0.73 | MYC (0.67) | ABCB1L3MBTL1POLBMYCMAX | |
| SCHEMBL528177 | 0.73 | MYC (0.67) | ABCB1L3MBTL1POLBMYCMAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |