Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CCR8 | P51685 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL6959493 | 0.91 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2TSHRTDP1 | |
| Oxalic Acid SCHEMBL6970867 | 0.91 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2CCR8TSHR | |
| SCHEMBL6970479 | 0.87 | HRH1 (0.41) | KDM4EALDH1A1SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL6964105 | 0.86 | LMNA (0.41) | ALDH1A1SMN1; SMN2KMT2AHTT | |
| Oxalic Acid SCHEMBL6959081 | 0.81 | ALDH1A1 (0.49) | KDM4EALDH1A1SMN1; SMN2KMT2ATDP1 | |
| Oxalic Acid SCHEMBL6964376 | 0.81 | ALDH1A1 (0.49) | KDM4EALDH1A1SMN1; SMN2KMT2ATDP1 | |
| SCHEMBL6960640 | 0.80 | TBXA2R (0.42) | — | |
| Hydrochloric Acid SCHEMBL6962970 | 0.80 | — | — | |
| SCHEMBL6955699 | 0.79 | SIGMAR1 (0.50) | KDM4EALDH1A1SMN1; SMN2TSHRKMT2A | |
| SCHEMBL6964102 | 0.79 | KDM4E (0.56) | KDM4EALDH1A1SMN1; SMN2CCR8HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934313-B1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK AS (DK) | 2003-05-14 | — | — | EP | disclosed |
| US-6004983-A | ANALGESICS; ANTIINFLAMMATORY, ANTIARTHRITIC AND ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DE) | 1999-12-21 | — | — | US | disclosed |
| EP-0934313-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998015549-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-04-16 | — | — | WO | disclosed |