Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7080025 | 0.92 | CYP1A2 (0.36) | ALDH1A1KDM4EPTGDR2PGRADORA3 | |
| SCHEMBL6966257 | 0.92 | TLR7 (0.35) | ALDH1A1KDM4EPLA2G2APTGDR2TLR7 | |
| SCHEMBL6967024 | 0.92 | ALDH1A1 (0.35) | ALDH1A1KDM4EPLA2G2APTGDR2TLR7 | |
| SCHEMBL6969000 | 0.91 | S1PR3 (0.36) | PLA2G2ANPC1RAB9A | |
| SCHEMBL6970942 | 0.91 | MAPT (0.35) | ALDH1A1KDM4EPLA2G2ATP53NPC1 | |
| SCHEMBL6961563 | 0.91 | S1PR3 (0.37) | PLA2G2ATLR7 | |
| SCHEMBL7081480 | 0.91 | ADRA1D (0.34) | PLA2G2ATLR7TP53NPC1RAB9A | |
| SCHEMBL7086919 | 0.90 | TLR7 (0.37) | ALDH1A1KDM4EPLA2G2APTGDR2TLR7 | |
| SCHEMBL7080059 | 0.89 | CFTR (0.38) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6974553 | 0.87 | HRH1 (0.34) | ALDH1A1KDM4EPTGDR2TLR7TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |