Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 15/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969000 | 0.94 | S1PR3 (0.36) | S1PR3PLA2G2AGRM5 | |
| SCHEMBL6968357 | 0.93 | S1PR3 (0.37) | S1PR3PPARGPPARA | |
| SCHEMBL6972492 | 0.93 | S1PR3 (0.38) | S1PR3PLA2G2A | |
| SCHEMBL7084640 | 0.93 | S1PR3 (0.39) | S1PR3PLA2G2ATLR7GRM5 | |
| SCHEMBL6972895 | 0.91 | S1PR3 (0.37) | S1PR3PLA2G2ATLR7 | |
| SCHEMBL6967466 | 0.91 | ALDH1A1 (0.33) | PLA2G2ATLR7 | |
| SCHEMBL7081480 | 0.90 | ADRA1D (0.34) | S1PR3PLA2G2ATLR7GRM5 | |
| SCHEMBL7081701 | 0.88 | S1PR3 (0.34) | S1PR3TLR7 | |
| SCHEMBL6970942 | 0.87 | MAPT (0.35) | PLA2G2AGRM5 | |
| SCHEMBL6973461 | 0.87 | S1PR3 (0.39) | S1PR3GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |