Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.30 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969157 | 1.00 | ADRA1D (0.32) | ADRA1DS1PR3ALDH1A1AGTR1TP53 | |
| SCHEMBL6971733 | 0.93 | GRM5 (0.35) | ADRA1DS1PR3ALDH1A1AGTR1TP53 | |
| SCHEMBL6971738 | 0.93 | GRM5 (0.35) | ADRA1DS1PR3ALDH1A1AGTR1TP53 | |
| SCHEMBL7085317 | 0.89 | ALDH1A1 (0.34) | S1PR3ALDH1A1TP53ALOX5APKDM4E | |
| SCHEMBL7085318 | 0.89 | ALDH1A1 (0.34) | S1PR3ALDH1A1TP53ALOX5APKDM4E | |
| SCHEMBL7084149 | 0.89 | S1PR3 (0.34) | S1PR3ALDH1A1NOX4ALOX5APKDM4E | |
| SCHEMBL7084152 | 0.89 | S1PR3 (0.34) | S1PR3ALDH1A1NOX4ALOX5APKDM4E | |
| SCHEMBL6973236 | 0.87 | ALDH1A1 (0.35) | ADRA1DS1PR3ALDH1A1AGTR1TP53 | |
| SCHEMBL6969251 | 0.85 | GRIN1 (0.38) | S1PR3ALDH1A1KMT2ANOX4MAPT | |
| SCHEMBL6969252 | 0.85 | GRIN1 (0.38) | S1PR3ALDH1A1KMT2ANOX4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |