Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970424 | 0.89 | ALDH1A1 (0.48) | BRD4MAPTTDP1MEN1KMT2A | |
| SCHEMBL6970905 | 0.87 | ALDH1A1 (0.47) | BRD4MAPTTDP1MEN1KMT2A | |
| SCHEMBL6955057 | 0.87 | BRD4 (0.57) | BRD4MAPTTDP1MEN1KMT2A | |
| SCHEMBL6964190 | 0.82 | BRD4 (0.60) | BRD4NPSR1HPGDHTTL3MBTL1 | |
| SCHEMBL6969301 | 0.81 | BRD4 (0.54) | BRD4MAPTTDP1MEN1KMT2A | |
| SCHEMBL6202811 | 0.80 | BRD4 (0.60) | BRD4MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL6201929 | 0.80 | BRD4 (0.60) | BRD4NPSR1HTTCRBNALDH1A1 | |
| SCHEMBL7346893 | 0.78 | MEN1 (0.68) | MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6966939 | 0.77 | TUBB4A (0.46) | BRD4MAPTTDP1MEN1KMT2A | |
| SCHEMBL6971322 | 0.76 | ALDH1A1 (0.60) | BRD4MAPTTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |