Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | BRD4 | O60885 | 6/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955057 | 0.90 | BRD4 (0.57) | ALDH1A1MAPTTDP1HTTMAPK1 | |
| SCHEMBL6962591 | 0.79 | HTT (0.71) | ALDH1A1MAPTTDP1HTTMAPK1 | |
| SCHEMBL6966939 | 0.79 | TUBB4A (0.46) | ALDH1A1MAPTTDP1HTTMAPK1 | |
| SCHEMBL6954979 | 0.78 | TUBB4A (0.45) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL6969301 | 0.76 | BRD4 (0.54) | ALDH1A1MAPTTDP1HTTMAPK1 | |
| SCHEMBL6970210 | 0.76 | BRD4 (0.59) | ALDH1A1MAPTTDP1HTTMAPK1 | |
| SCHEMBL7348484 | 0.76 | PDE4A (0.53) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7333735 | 0.75 | AVPR1A (0.66) | — | |
| SCHEMBL7348149 | 0.74 | PDE4B (0.69) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL9375233 | 0.73 | HTT (1.00) | ALDH1A1HTTMAPK1NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |