Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970424 | 0.90 | ALDH1A1 (0.48) | ALDH1A1KDM4EL3MBTL1BLMMAPT | |
| SCHEMBL6954979 | 0.88 | TUBB4A (0.45) | ALDH1A1MAPTMEN1KMT2ABRD4 | |
| SCHEMBL6970210 | 0.87 | BRD4 (0.59) | ALDH1A1KDM4EL3MBTL1BLMMAPT | |
| SCHEMBL6971115 | 0.85 | BRD4 (0.45) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL6966939 | 0.79 | TUBB4A (0.46) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL6971003 | 0.76 | BRD4 (0.45) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL6971266 | 0.75 | L3MBTL1 (0.44) | ALDH1A1L3MBTL1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL6962161 | 0.75 | LMNA (0.49) | ALDH1A1KDM4EL3MBTL1BLMMAPT | |
| SCHEMBL6955057 | 0.74 | BRD4 (0.57) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL6970387 | 0.72 | BRD4 (0.52) | ALDH1A1KDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |