Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960079 | 0.89 | ALDH1A1 (0.48) | DRD2DRD4DRD3GRIN1GRIN2B | |
| SCHEMBL6958687 | 0.85 | DRD3 (0.46) | DRD2DRD4DRD3GRIN1GRIN2B | |
| SCHEMBL6955542 | 0.83 | ALDH1A1 (0.43) | DRD2DRD4DRD3L3MBTL1NPC1 | |
| SCHEMBL6969761 | 0.82 | L3MBTL1 (0.43) | DRD2DRD4DRD3GRIN1GRIN2B | |
| SCHEMBL6969126 | 0.80 | L3MBTL1 (0.45) | DRD2DRD4DRD3L3MBTL1NPC1 | |
| SCHEMBL7140109 | 0.79 | L3MBTL1 (0.45) | L3MBTL1NPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL6955643 | 0.77 | L3MBTL1 (0.46) | L3MBTL1NPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL6964416 | 0.76 | DRD2 (0.50) | DRD2DRD4DRD3GRIN1GRIN2B | |
| SCHEMBL6970758 | 0.76 | ALDH1A1 (0.45) | L3MBTL1HTTALDH1A1MAPT | |
| SCHEMBL6969043 | 0.75 | DRD3 (0.47) | DRD2DRD4DRD3L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |