Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.30 |
| ▸ | WNT3A | P56704 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3633653 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2RXFP1HPGDHTTLMNA | |
| SCHEMBL6464252 | 0.77 | CFTR (0.44) | SMN1; SMN2RXFP1HPGDHTTLMNA | |
| SCHEMBL6971332 | 0.77 | SCD (0.33) | SMN1; SMN2RXFP1HPGDHTTLMNA | |
| SCHEMBL9625067 | 0.67 | KDM4E (0.50) | HPGDLMNAMAPK1ESR2 | |
| SCHEMBL6969828 | 0.63 | TP53 (0.36) | SMN1; SMN2HPGDHTTLMNATSHR | |
| SCHEMBL21128544 | 0.62 | KMT2A (0.42) | SMN1; SMN2HPGDHTTTSHRRAB9A | |
| SCHEMBL22893863 | 0.60 | LOXL2 (0.33) | — | |
| Bicarbonate SCHEMBL28887905 | 0.58 | L3MBTL1 (0.44) | SMN1; SMN2HPGDKMT2AMAPK1ESR2 | |
| SCHEMBL11805874 | 0.57 | CES2 (0.75) | HPGDGAAMEN1KMT2ACES2 | |
| SCHEMBL4446378 | 0.57 | CES2 (0.45) | HPGDLMNASCDNPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |