Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1970294 | 0.83 | MEN1 (0.44) | ALDH1A1MAPTLMNAKMT2ANPSR1 | |
| SCHEMBL11770256 | 0.82 | ESR1 (0.49) | ALDH1A1MAPTKDM4ELMNAKMT2A | |
| SCHEMBL27971666 | 0.81 | MAPT (0.47) | ALDH1A1MAPTKDM4EMAPK1LMNA | |
| SCHEMBL3232287 | 0.81 | CA12 (0.45) | ALDH1A1MAPTLMNANPSR1TSHR | |
| SCHEMBL2554850 | 0.81 | MAPT (0.47) | ALDH1A1MAPTKDM4EMAPK1LMNA | |
| SCHEMBL1516027 | 0.80 | MMP8 (0.53) | MAPTKDM4ELMNAKMT2ATSHR | |
| SCHEMBL6669586 | 0.79 | ALOX15 (0.47) | ALDH1A1MAPTKDM4ELMNAKMT2A | |
| SCHEMBL1970366 | 0.79 | MEN1 (0.46) | ALDH1A1MAPK1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL24129414 | 0.79 | SLC6A4 (0.48) | ALDH1A1MAPTKDM4EMAPK1SLC6A4 | |
| SCHEMBL4038007 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4EMAPK1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107756-A4 | NOVEL ISOXAZOLINONE ANTIBACTERIAL AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2003-02-26 | — | — | EP | disclosed |
| US-20020094984-A1 | Novel isoxazolinone antibacterial agents | SNYDER LAWRENCE B (US) | 2002-07-18 | — | — | US | disclosed |
| US-6420349-B1 | POTENT ANTIBIOTIC ACTIVE AGAINST GRAM-POSITIVE BACTERIA; ANIMAL FEED;FOOD PRESERVATIVES; WATERBASED PAINTS; WHITE WATER OF PAPER MILLS; DISINFECTANTS FOR MEDICAL AND DENTAL EQUIPMENT | BRISTOL-MYERS SQUIBB COMPANY | 2002-07-16 | — | — | US | disclosed |
| EP-1107756-A1 | NOVEL ISOXAZOLINONE ANTIBACTERIAL AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000010566-A1 | NOVEL ISOXAZOLINONE ANTIBACTERIAL AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020094984-A1 | Novel isoxazolinone antibacterial agents | RPS4X, RPS4Y1, CYP51A1 | ALDH1A1 261/4885MAPT 4521/4885KDM4E 3648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.