Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MLNR | O43193 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1030905 | 0.84 | APP (0.48) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6960847 | 0.84 | ACHE (0.52) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL5387739 | 0.80 | LMNA (0.44) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6960838 | 0.78 | SMN1; SMN2 (0.43) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL8715421 | 0.78 | ALDH1A1 (0.40) | LMNAALDH1A1HSPB1TSHRHSD17B10 | |
| SCHEMBL4834040 | 0.77 | HSPB1 (0.50) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL457863 | 0.76 | HSPB1 (0.68) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL192974 | 0.75 | HTT (0.44) | LMNAALDH1A1MEN1KMT2AMAPT | |
| Diphenylether SCHEMBL28998326 | 0.74 | ALDH1A1 (0.73) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8115250 | 0.73 | HPGD (0.40) | LMNAALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1182123-C | Substituted bicyclic derivatives useful as anticancer agents | �Ʒ� | 2004-12-29 | — | — | CN | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| CN-1333758-A | Substituted bicyclic derivatives useful as anticancer agents | PFIZER PROD INC (US) | 2002-01-30 | — | — | CN | disclosed |