Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972654 | 0.78 | LMNA (0.44) | SMN1; SMN2TBXA2RMAPTALDH1A1MEN1 | |
| SCHEMBL8115250 | 0.77 | HPGD (0.40) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4378038 | 0.76 | HSPB1 (0.56) | SMN1; SMN2TBXA2RMAPTALDH1A1MEN1 | |
| SCHEMBL6960847 | 0.76 | ACHE (0.52) | SMN1; SMN2TBXA2RMAPTALDH1A1MEN1 | |
| SCHEMBL22966296 | 0.75 | TBXA2R (0.56) | SMN1; SMN2TBXA2RMAPTALDH1A1MEN1 | |
| SCHEMBL192974 | 0.74 | HTT (0.44) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8715421 | 0.73 | ALDH1A1 (0.40) | ALDH1A1HSD17B10TSHRTDP1ACHE | |
| SCHEMBL10422274 | 0.73 | HSD17B10 (0.58) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL1030905 | 0.73 | APP (0.48) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8973686 | 0.72 | HSPB1 (0.69) | SMN1; SMN2TBXA2RMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |