Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MYOC | Q99972 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1030905 | 0.88 | APP (0.48) | MAPTHTTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6972654 | 0.84 | LMNA (0.44) | HSD17B10MAPTHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL5387739 | 0.84 | LMNA (0.44) | MAPTHTTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8695353 | 0.79 | HSD17B10 (0.75) | ACHEHSD17B10MAPTHTTALDH1A1 | |
| SCHEMBL192974 | 0.76 | HTT (0.44) | ACHEHSD17B10MAPTHTTALDH1A1 | |
| SCHEMBL6960838 | 0.76 | SMN1; SMN2 (0.43) | ACHEHSD17B10MAPTHTTALDH1A1 | |
| SCHEMBL8715421 | 0.76 | ALDH1A1 (0.40) | ACHEHSD17B10ALDH1A1LMNAHSPB1 | |
| SCHEMBL10593836 | 0.73 | ACHE (0.52) | ACHEMAPTALDH1A1NPSR1KMT2A | |
| SCHEMBL4135373 | 0.72 | PTGS2 (0.47) | ACHEHSD17B10MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL16950956 | 0.72 | MAPT (0.41) | ACHEHSD17B10MAPTHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |