Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965890 | 0.83 | KMT2A (0.44) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL6978730 | 0.81 | KMT2A (0.70) | KMT2AMEN1ATMPIN1PIN4 | |
| SCHEMBL6978776 | 0.77 | KMT2A (0.70) | KMT2AMEN1ATMPIN1PIN4 | |
| SCHEMBL9323818 | 0.76 | KMT2A (0.76) | KMT2AMEN1ATMPTPN1ALDH1A1 | |
| SCHEMBL9323487 | 0.73 | KMT2A (0.65) | KMT2AMEN1ATMPIN1PIN4 | |
| SCHEMBL9325767 | 0.73 | KMT2A (0.77) | KMT2AMEN1ATMPIN1PIN4 | |
| SCHEMBL9323617 | 0.72 | KMT2A (0.73) | KMT2AMEN1ATMPIN1PIN4 | |
| SCHEMBL6061073 | 0.72 | PIN1 (0.62) | KMT2APIN1PIN4ALDH1A1MAPT | |
| SCHEMBL8872080 | 0.71 | KMT2A (0.61) | KMT2AMEN1ATMPIN1PIN4 | |
| SCHEMBL9323944 | 0.71 | KMT2A (0.72) | KMT2AMEN1ATMPIN1PIN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718289-B1 | Novel parabanic acid derivatives as aldose reductase inhibitors | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2003-03-05 | — | — | EP | disclosed |
| EP-0718289-A1 | Novel parabanic acid derivatives as aldose reductase inhibitors | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1996-06-26 | — | — | EP | disclosed |