Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 3/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973846 | 0.93 | — | — | |
| SCHEMBL7084647 | 0.91 | ALDH1A1 (0.38) | SLC6A9CSNK2A2CSNK2BKMT2A | |
| SCHEMBL7086009 | 0.90 | SLC6A9 (0.30) | SLC6A9 | |
| SCHEMBL7081545 | 0.90 | CSNK2A2 (0.34) | SLC6A9CSNK2A2CSNK2BFNTAFNTB | |
| SCHEMBL6975782 | 0.90 | CDK5 (0.33) | — | |
| SCHEMBL7084598 | 0.89 | ADRB2 (0.33) | SLC6A9CSNK2A2CSNK2BFNTAFNTB | |
| SCHEMBL7086458 | 0.88 | TP53 (0.36) | SLC6A9ALOX12TP53RXFP1 | |
| SCHEMBL6967395 | 0.87 | MEN1 (0.35) | RXFP1KMT2ASLC2A1 | |
| SCHEMBL6973420 | 0.87 | SMN1; SMN2 (0.35) | SLC6A9TP53RXFP1KMT2A | |
| SCHEMBL8799715 | 0.86 | PDE4D (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |