Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7084598 | 0.90 | ADRB2 (0.33) | PDE4DPDE4B | |
| SCHEMBL7081545 | 0.87 | CSNK2A2 (0.34) | PDE4DPDE4BPOLBTYMS | |
| SCHEMBL6973004 | 0.86 | SLC6A9 (0.32) | — | |
| SCHEMBL7079911 | 0.85 | SLC2A1 (0.34) | PDE4DPDE4BPOLBTYMS | |
| SCHEMBL6970653 | 0.81 | — | — | |
| SCHEMBL6972366 | 0.81 | ALDH1A1 (0.37) | — | |
| SCHEMBL7084286 | 0.79 | MAPK13 (0.30) | — | |
| SCHEMBL597335 | 0.78 | MEN1 (0.31) | — | |
| SCHEMBL7080940 | 0.78 | MEN1 (0.31) | — | |
| SCHEMBL6967066 | 0.78 | CYP3A4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |