Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
| ▸ | FNTA | P49354 | 1/20 | 0.30 |
| ▸ | FNTB | P49356 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970653 | 0.92 | — | — | |
| SCHEMBL6972366 | 0.91 | ALDH1A1 (0.37) | ADRB2ADRB1ADRB3 | |
| SCHEMBL8799715 | 0.90 | PDE4D (0.32) | PDE4DPDE4B | |
| SCHEMBL7084286 | 0.89 | MAPK13 (0.30) | — | |
| SCHEMBL6973004 | 0.89 | SLC6A9 (0.32) | SLC6A9CSNK2A2CSNK2BFNTAFNTB | |
| SCHEMBL6967066 | 0.89 | CYP3A4 (0.32) | — | |
| SCHEMBL7087608 | 0.87 | TP53 (0.35) | ADRB2ADRB1ADRB3SLC6A9 | |
| SCHEMBL7081545 | 0.86 | CSNK2A2 (0.34) | PDE4DPDE4BSLC6A9CSNK2A2CSNK2B | |
| SCHEMBL6960274 | 0.86 | MAPT (0.34) | ADRB2ADRB1ADRB3SLC6A9 | |
| SCHEMBL7080474 | 0.86 | CSNK2A2 (0.34) | ADRB2ADRB1ADRB3PDE4DPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |