Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | HTR1B | P28222 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973290 | 0.81 | EPHX1 (0.61) | KMT2AEPHX1PTPN2PTPN1MEN1 | |
| SCHEMBL9404055 | 0.79 | ALDH1A1 (0.61) | EPHX1TAAR1ALDH1A1EPHX2 | |
| SCHEMBL6969542 | 0.79 | MGLL (0.62) | KMT2APTPN2PTPN1MEN1ALDH1A1 | |
| SCHEMBL24663619 | 0.76 | ACHE (0.64) | KMT2AEPHX1PTPN2PTPN1MEN1 | |
| SCHEMBL7499151 | 0.76 | ACHE (0.59) | KMT2AEPHX1PTPN2PTPN1MEN1 | |
| SCHEMBL6970106 | 0.76 | ACHE (0.65) | KMT2APOLBMEN1ALDH1A1ACHE | |
| SCHEMBL13472207 | 0.75 | ACHE (0.57) | KMT2AEPHX1PTPN2PTPN1MEN1 | |
| SCHEMBL6981291 | 0.74 | MGLL (0.70) | KMT2AEPHX1MEN1EPHX2MGLL | |
| SCHEMBL1673861 | 0.74 | MAPT (0.73) | KMT2AEPHX1PTPN2PTPN1MEN1 | |
| SCHEMBL13636742 | 0.73 | MEN1 (0.60) | KMT2AEPHX1PTPN2PTPN1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892795-B1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMA (JP) | 2003-01-08 | — | — | EP | disclosed |
| EP-0892795-A1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997038992-A1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-10-23 | — | — | WO | disclosed |