Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3349691 | 0.83 | TDP1 (0.42) | CES2CES1ALDH1A1ALOX15NPC1 | |
| SCHEMBL27662352 | 0.81 | L3MBTL1 (0.45) | CES2CES1ALDH1A1ALOX15NPC1 | |
| SCHEMBL28248518 | 0.81 | ALDH1A1 (0.47) | CES2CES1ALDH1A1ALOX15NPC1 | |
| SCHEMBL2091486 | 0.77 | DDB1 (0.47) | CES2CES1ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL2098346 | 0.74 | NPSR1 (0.54) | CES2CES1ALDH1A1ALOX15NPC1 | |
| SCHEMBL6002861 | 0.72 | CES2 (0.33) | CES2CES1ALDH1A1ALOX15NPC1 | |
| SCHEMBL163434 | 0.71 | ACHE (0.39) | CES2CES1ALDH1A1ALOX15NPC1 | |
| SCHEMBL29523028 | 0.71 | ACHE (0.39) | CES2CES1ALDH1A1ALOX15NPC1 | |
| SCHEMBL15735249 | 0.70 | L3MBTL1 (0.35) | CES2CES1ALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL6960658 | 0.70 | NPSR1 (0.48) | CES2CES1ALDH1A1ALOX15NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |