Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 6/20 | 0.39 |
| ▸ | MMP1 | P03956 | 3/20 | 0.39 |
| ▸ | MMP3 | P08254 | 3/20 | 0.39 |
| ▸ | MMP7 | P09237 | 3/20 | 0.39 |
| ▸ | MMP9 | P14780 | 3/20 | 0.39 |
| ▸ | MMP8 | P22894 | 3/20 | 0.39 |
| ▸ | MMP13 | P45452 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | YAP1 | P46937 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969250 | 0.93 | NPC1 (0.43) | KDM4EPKMLMNATGFBR1ALDH1A1 | |
| SCHEMBL7943550 | 0.92 | TGFBR1 (0.43) | KDM4EPKMLMNATGFBR1TP53 | |
| SCHEMBL7953690 | 0.91 | KDM4E (0.40) | KDM4EPKMLMNATGFBR1ALDH1A1 | |
| SCHEMBL7943621 | 0.87 | KDM4E (0.40) | KDM4EPKMLMNATGFBR1MMP13 | |
| SCHEMBL6975040 | 0.86 | LMNA (0.42) | KDM4EPKMLMNATP53THRB | |
| SCHEMBL6964406 | 0.84 | KDM4E (0.41) | KDM4EPKMLMNATGFBR1ALDH1A1 | |
| SCHEMBL6966451 | 0.82 | KDM4E (0.45) | KDM4EPKMLMNATP53YAP1 | |
| SCHEMBL6966742 | 0.79 | YAP1 (0.49) | KDM4EPKMLMNATGFBR1TP53 | |
| SCHEMBL6973933 | 0.79 | KDM4E (0.41) | KDM4EPKMLMNAALDH1A1TP53 | |
| SCHEMBL6964195 | 0.76 | YAP1 (0.45) | KDM4EPKMLMNATGFBR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098878-B1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | CEPHALON FRANCE (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-6333338-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | LABORATOIRE L. LAFON (FR) | 2001-12-25 | — | — | US | disclosed |