Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | YAP1 | P46937 | 2/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971137 | 0.93 | KDM4E (0.41) | ALDH1A1MAPTKDM4EPKMLMNA | |
| SCHEMBL7953690 | 0.89 | KDM4E (0.40) | ALDH1A1KDM4EPKMLMNAYAP1 | |
| SCHEMBL6975040 | 0.88 | LMNA (0.42) | MAPTKDM4EPKMLMNAGPR119 | |
| SCHEMBL7943550 | 0.88 | TGFBR1 (0.43) | KDM4EPKMLMNAGPR119YAP1 | |
| SCHEMBL7943621 | 0.87 | KDM4E (0.40) | MAPTKDM4EPKMLMNAGPR119 | |
| SCHEMBL6964406 | 0.87 | KDM4E (0.41) | ALDH1A1L3MBTL1KDM4EPKMLMNA | |
| SCHEMBL6966451 | 0.83 | KDM4E (0.45) | MAPTL3MBTL1KDM4EPKMLMNA | |
| SCHEMBL6973933 | 0.80 | KDM4E (0.41) | ALDH1A1MAPTL3MBTL1KDM4EPKM | |
| SCHEMBL6975227 | 0.77 | YAP1 (0.48) | ALDH1A1MAPTMAPK1HTTL3MBTL1 | |
| SCHEMBL6976104 | 0.77 | YAP1 (0.47) | MAPTMAPK1HTTL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098878-B1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | CEPHALON FRANCE (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-6333338-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | LABORATOIRE L. LAFON (FR) | 2001-12-25 | — | — | US | disclosed |