Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969475 | 0.94 | ALDH1A1 (0.37) | ADRA1DSLC16A3GABRA1GABRA5S1PR3 | |
| SCHEMBL6969211 | 0.93 | KMT2A (0.34) | SLC16A3GABRA1GABRA5S1PR3KMT2A | |
| SCHEMBL6966178 | 0.93 | ADRA1D (0.36) | ADRA1DGABRA1GABRA5S1PR3KMT2A | |
| SCHEMBL6957033 | 0.93 | ADRA1D (0.37) | ADRA1DSLC16A3TLR7GABRA1GABRA5 | |
| SCHEMBL6966597 | 0.91 | FKBP1A (0.35) | ADRA1DTLR7GABRA1GABRA5S1PR3 | |
| SCHEMBL6961932 | 0.91 | PIM1 (0.33) | KMT2AMEN1 | |
| SCHEMBL6973065 | 0.91 | GRIN1 (0.35) | TLR7S1PR3PKM | |
| SCHEMBL6960297 | 0.90 | MDM2 (0.34) | TLR7GABRA1GABRA5S1PR3KMT2A | |
| SCHEMBL7085225 | 0.88 | GRM5 (0.33) | SLC16A3TLR7GABRA1GABRA5S1PR3 | |
| SCHEMBL7083459 | 0.88 | GRIN1 (0.35) | S1PR3KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |