Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.32 |
| ▸ | VCP | P55072 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14439828 | 0.89 | TDP1 (0.40) | TDP1KMT2AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL6957630 | 0.85 | DHODH (0.39) | TDP1ALDH1A1HTTMAPTPOLB | |
| SCHEMBL14439857 | 0.85 | DHODH (0.39) | TDP1ALDH1A1HTTMAPTPOLB | |
| SCHEMBL5853114 | 0.85 | TDP1 (0.37) | TDP1ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL6969568 | 0.85 | P2RX3 (0.37) | TDP1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL6962868 | 0.85 | P2RX3 (0.35) | TDP1ALDH1A1HTTP2RX3GAA | |
| SCHEMBL6969396 | 0.84 | TDP1 (0.37) | TDP1KMT2AP2RX3SLC5A2ADAMTS5 | |
| SCHEMBL7087497 | 0.83 | P2RX3 (0.36) | TDP1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL6966496 | 0.83 | VCP (0.37) | TDP1MAPTSMN1; SMN2L3MBTL1TP53 | |
| SCHEMBL27397423 | 0.82 | TDP1 (0.37) | TDP1ALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |