Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 5/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6785472 | 0.96 | MMP13 (0.44) | MMP13ADAMTS4CYP3A4LMNAPOLB | |
| SCHEMBL6788336 | 0.93 | MMP13 (0.44) | MMP13ADAMTS4CYP3A4LMNAPOLB | |
| SCHEMBL6788003 | 0.84 | MMP13 (0.43) | MMP13ADAMTS4CYP3A4LMNAPOLB | |
| SCHEMBL6786249 | 0.83 | ADAMTS4 (0.47) | MMP13ADAMTS4CYP3A4LMNAPOLB | |
| SCHEMBL6783061 | 0.76 | MMP2 (0.45) | MMP13ADAMTS4CYP3A4LMNAPOLB | |
| SCHEMBL6974852 | 0.72 | ADAMTS4 (0.43) | MMP13ADAMTS4CYP3A4LMNAPOLB | |
| SCHEMBL6969646 | 0.72 | HDAC6 (0.43) | LMNAPOLBALDH1A1SLC6A7KCNH2 | |
| SCHEMBL6782110 | 0.71 | MMP13 (0.44) | MMP13ADAMTS4CYP3A4LMNAPOLB | |
| SCHEMBL6782104 | 0.71 | MMP13 (0.44) | MMP13ADAMTS4CYP3A4LMNAPOLB | |
| SCHEMBL7090534 | 0.71 | ADAM10 (0.42) | ADAMTS4LMNAPOLBMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030216404-A1 | Hydroxamic acid derivatives | HANNAH DUNCAN ROBERT (GB) | 2003-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216404-A1 | Hydroxamic acid derivatives | ADAM17, ADAM10, ADAM33 | MMP13 29/4885ADAMTS4 10/4885CYP3A4 3171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.