Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CCR10 | P46092 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984122 | 0.85 | F2 (0.42) | TDP1L3MBTL1KMT2AHDAC4HDAC1 | |
| SCHEMBL6985322 | 0.84 | GAA (0.41) | LSSKMT2AHDAC4HDAC1HDAC8 | |
| SCHEMBL6984463 | 0.83 | POLB (0.44) | KMT2AHDAC4HDAC1HDAC8ALDH1A1 | |
| SCHEMBL6981477 | 0.82 | GAA (0.38) | TDP1STAT3DPP8DPP9L3MBTL1 | |
| SCHEMBL6985050 | 0.82 | ALDH1A1 (0.39) | TDP1STAT3L3MBTL1LSSKMT2A | |
| SCHEMBL6974890 | 0.80 | DPP8 (0.37) | DPP8DPP9L3MBTL1KMT2ANPC1 | |
| SCHEMBL6985749 | 0.79 | ALDH1A1 (0.48) | TDP1L3MBTL1KMT2AGAAALDH1A1 | |
| SCHEMBL7411038 | 0.77 | PKM (0.43) | TDP1L3MBTL1KMT2AGAAALDH1A1 | |
| SCHEMBL6983851 | 0.77 | KCNJ1 (0.39) | TDP1DPP8DPP9L3MBTL1KMT2A | |
| SCHEMBL6984759 | 0.77 | LMNA (0.47) | KMT2AGAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |