Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.35 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6800906 | 0.77 | TDP1 (0.38) | MAPTTDP1KMT2AALDH1A1MEN1 | |
| SCHEMBL695031 | 0.76 | RAB9A (0.43) | MAPTADRA2AADRA2BADRA2CSLC2A1 | |
| SCHEMBL3156019 | 0.75 | MAPT (0.52) | MAPTADRA2AADRA2BADRA2CSLC2A1 | |
| SCHEMBL695700 | 0.75 | LMNA (0.40) | MAPTADRA2AADRA2BADRA2CSLC2A1 | |
| SCHEMBL6806454 | 0.71 | TDP1 (0.46) | MAPTTDP1KMT2AALDH1A1MEN1 | |
| SCHEMBL8974165 | 0.70 | NPC1 (0.53) | MAPTADRA2AADRA2BADRA2CSLC2A1 | |
| SCHEMBL7086023 | 0.70 | ALDH1A1 (0.47) | MAPTADRA2AADRA2BADRA2CSLC2A1 | |
| SCHEMBL28610542 | 0.69 | ALDH1A1 (0.53) | MAPTTDP1KMT2AALDH1A1MEN1 | |
| SCHEMBL28607197 | 0.69 | GPR35 (0.51) | MAPTADRA2AADRA2BADRA2CSLC2A1 | |
| SCHEMBL14880717 | 0.69 | TSHR (0.47) | MAPTTDP1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351939-A1 | COUPLER/DEVELOPER AND COUPLER/COUPLER HYBRID DYES AND COUPLER/DEVELOPER AND COUPLER/COUPLER HYBRID DYE INTERMEDIATES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002055500-A1 | COUPLER/DEVELOPER AND COUPLER/COUPLER HYBRID DYES AND COUPLER/DEVELOPER AND COUPLER/COUPLER HYBRID DYE INTERMEDIATES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-07-18 | — | — | WO | disclosed |