Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975602 | 1.00 | HTR1A (0.38) | HTR1ADRD3DRD2HTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL6984682 | 0.79 | DRD2 (0.58) | HTR1ADRD3DRD2HTR2AHTR7 | |
| SCHEMBL16986213 | 0.71 | ALDH1A1 (0.52) | HTR1ADRD3KMT2AALDH1A1HPGD | |
| SCHEMBL16986211 | 0.71 | ALDH1A1 (0.52) | HTR1ADRD3KMT2AALDH1A1HPGD | |
| SCHEMBL7475487 | 0.68 | RAB9A (0.49) | SRD5A2 | |
| SCHEMBL16986186 | 0.68 | ALDH1A1 (0.48) | HTR1ADRD3DRD2SIGMAR1KMT2A | |
| SCHEMBL16986185 | 0.68 | ALDH1A1 (0.48) | HTR1ADRD3DRD2SIGMAR1KMT2A | |
| Oxalic Acid SCHEMBL6969996 | 0.67 | KMT2A (0.46) | HTR2AKMT2AALDH1A1HPGDMAPT | |
| SCHEMBL6970002 | 0.67 | HTR2A (0.34) | HTR1ADRD2HTR2AHTR7SIGMAR1 | |
| SCHEMBL6890792 | 0.67 | DRD2 (0.41) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1065205-B1 | HETEROAROMATIC DERIVATIVES | TAISHO PHARMACEUTICAL CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-1207159-A1 | Aromaheterocyclic derivatives as dopamine D4 receptor antagonists | TAISHO PHARMACEUTICAL CO. LTD (JP) | 2002-05-22 | — | — | EP | disclosed |
| US-6291467-B1 | DOPAMINE D4 RECEPTOR ANTAGONIST COMPOUND HAVING AN ANTIPSYCHOTIC ACTION WITHOUT CAUSING EXTRAPYRAMIDAL DISEASES. | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-1065205-A1 | HETEROAROMATIC DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2001-01-03 | — | — | EP | disclosed |