Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967946 | 0.81 | F2 (0.38) | F2PRSS1BCHEACHE | |
| SCHEMBL6972547 | 0.81 | F2 (0.43) | F2 | |
| SCHEMBL6976769 | 0.79 | MAOB (0.44) | DPP4 | |
| SCHEMBL6976833 | 0.79 | F2 (0.36) | F2PRSS1 | |
| SCHEMBL6972814 | 0.79 | DPP4 (0.34) | LMNAPIK3CADPP4 | |
| SCHEMBL6976617 | 0.78 | SMYD3 (0.42) | LMNAALDH1A1SMN1; SMN2PIK3CDPIK3CA | |
| SCHEMBL6976473 | 0.77 | RAB9A (0.37) | LMNAF2ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL6976541 | 0.77 | MAOB (0.47) | LMNAALDH1A1MAPK1SMN1; SMN2DPP4 | |
| SCHEMBL6975942 | 0.76 | F2 (0.35) | F2ALDH1A1SMN1; SMN2 | |
| SCHEMBL6978874 | 0.75 | CTSK (0.43) | ALDH1A1MAPK1SMN1; SMN2PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833839-B1 | PEPTIDYL HETEROCYCLES USEFUL IN THE TREATMENT OF THROMBIN RELATED DISORDERS | ORTHO PHARMA CORP (US) | 2003-01-08 | — | — | EP | claimed |
| EP-0833839-B1 | PEPTIDYL HETEROCYCLES USEFUL IN THE TREATMENT OF THROMBIN RELATED DISORDERS | ORTHO PHARMA CORP (US) | 2003-01-08 | — | — | EP | disclosed |