Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975733 | 0.84 | HTR4 (0.48) | HTR1AADRA1DADRA1AADRA1BHTR1D | |
| SCHEMBL6973703 | 0.82 | CCR8 (0.48) | SIGMAR1 | |
| SCHEMBL6973699 | 0.82 | CCR8 (0.48) | SIGMAR1 | |
| SCHEMBL6628061 | 0.81 | HTR1A (0.54) | HTR1AADRA1DADRA1AADRA1BHTR1D | |
| SCHEMBL6972322 | 0.78 | DRD3 (0.37) | HTR1ADRD2 | |
| SCHEMBL6972325 | 0.78 | DRD3 (0.37) | HTR1ADRD2 | |
| SCHEMBL6978353 | 0.72 | ADRB3 (0.46) | HTR1AADRA1DADRA1AADRA1BHTR1D | |
| SCHEMBL6976945 | 0.72 | HTR4 (0.57) | HTR1AHTR1DHTR2AHTR7HTR2B | |
| SCHEMBL6973562 | 0.70 | HTR4 (0.46) | HTR1AADRA1DADRA1AADRA1BHTR1D | |
| SCHEMBL6977618 | 0.69 | HTR4 (0.46) | HTR1AADRA1DADRA1AADRA1BHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051413-B1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2003-06-04 | — | — | EP | claimed |