Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 4/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.37 |
| ▸ | CDK9 | P50750 | 2/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981421 | 0.87 | ALDH1A1 (0.42) | CNR1ALDH1A1MAPTNPSR1 | |
| SCHEMBL6981336 | 0.77 | CCNT1 (0.42) | CNR1ALDH1A1MAPTCNR2CCNT1 | |
| SCHEMBL6979608 | 0.76 | CAMK2D (0.35) | CNR1CA12CA1CA2CA9 | |
| SCHEMBL6985899 | 0.75 | MAPT (0.40) | CNR1ALDH1A1MAPTNPSR1CNR2 | |
| SCHEMBL6980479 | 0.75 | CAMK2D (0.45) | CCNT1CDK9CCNA2CDK2 | |
| SCHEMBL6981135 | 0.73 | ALDH1A1 (0.40) | CNR1CA12CA1CA2CA9 | |
| SCHEMBL7005339 | 0.73 | CAMK2D (0.55) | — | |
| SCHEMBL7005879 | 0.73 | PIM1 (0.48) | CNR1MAPTCCNT1CDK9CCNA2 | |
| Acetic Acid SCHEMBL7007558 | 0.72 | CAMK2D (0.53) | — | |
| Trifluoroacetic Acid SCHEMBL6985258 | 0.72 | CAMK2D (0.39) | CA12CA1CA2CA9CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095039-B1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2003-08-27 | — | — | EP | disclosed |
| US-6346625-B1 | ENZYME INHIBITORS FOR PROTEIN KINASES | ASTRAZENECA AB (SE) | 2002-02-12 | — | — | US | disclosed |