Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972305 | 0.93 | FPR3 (0.44) | ALDH1A1SMN1; SMN2OPRD1MAPTOPRK1 | |
| SCHEMBL6967337 | 0.88 | OPRD1 (0.39) | OPRD1OPRK1OPRM1OPRL1 | |
| SCHEMBL6966745 | 0.87 | HTT (0.41) | ALDH1A1SMN1; SMN2ACKR3OPRD1OPRK1 | |
| SCHEMBL6969075 | 0.87 | OPRD1 (0.38) | OPRD1OPRK1OPRM1OPRL1 | |
| SCHEMBL6978119 | 0.86 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2ACKR3OPRD1MAPT | |
| SCHEMBL6973626 | 0.86 | OPRD1 (0.40) | ALDH1A1OPRD1OPRK1OPRM1LMNA | |
| SCHEMBL6969796 | 0.86 | OPRD1 (0.42) | ALDH1A1OPRD1OPRK1OPRM1LMNA | |
| SCHEMBL6980217 | 0.85 | ACHE (0.43) | ALDH1A1SMN1; SMN2OPRD1 | |
| SCHEMBL6971228 | 0.85 | ADRA1A (0.44) | ACKR3OPRD1OPRK1OPRM1KMT2A | |
| SCHEMBL6974993 | 0.84 | CCR3 (0.41) | ALDH1A1OPRD1OPRK1OPRM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202984-B1 | DIPHENYL-PIPERIDINE DERIVATE | ASTRAZENECA UK LTD (GB) | 2003-03-05 | — | — | EP | claimed |