Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGAV | P06756 | 2/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984536 | 0.79 | GLO1 (0.48) | PARP14ITGB3ITGAVSRCHPGD | |
| SCHEMBL6984823 | 0.74 | HTR6 (0.48) | SRCLMNAKDM4EALDH1A1GAA | |
| SCHEMBL6985112 | 0.73 | ALDH1A1 (0.64) | LMNAKDM4EALDH1A1GAAMAPT | |
| SCHEMBL6981244 | 0.72 | BRD4 (0.49) | BRD4HPGDLMNAKDM4EALDH1A1 | |
| SCHEMBL28028253 | 0.72 | SRC (0.45) | SRCADRA1AHPGDLMNAKDM4E | |
| SCHEMBL1010061 | 0.72 | HPGD (0.39) | HPGDLMNAALDH1A1GAAMAPT | |
| SCHEMBL379494 | 0.71 | SRC (0.47) | SRCADRA1AHPGDKDM4EALDH1A1 | |
| SCHEMBL6986762 | 0.71 | ALDH1A1 (0.53) | LMNAKDM4EALDH1A1GAAMAPT | |
| SCHEMBL6985321 | 0.71 | ALDH1A1 (0.48) | SRCHPGDLMNAKDM4EALDH1A1 | |
| SCHEMBL6982220 | 0.71 | ALDH1A1 (0.64) | BRD4LMNAKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |