Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984823 | 0.88 | HTR6 (0.48) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL6985321 | 0.87 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL6982220 | 0.87 | ALDH1A1 (0.64) | ALDH1A1GAAKDM4ELMNAHTT | |
| SCHEMBL6985112 | 0.87 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL6976544 | 0.81 | MEN1 (0.53) | ALDH1A1MEN1KMT2AGLO1LMNA | |
| SCHEMBL6983864 | 0.80 | SLC40A1 (0.50) | ALDH1A1MAPTGAAKDM4ELMNA | |
| SCHEMBL6974140 | 0.80 | WDR5 (0.45) | ALDH1A1GAAKDM4ELMNAHTT | |
| SCHEMBL30553402 | 0.78 | SLC40A1 (0.43) | ALDH1A1GAAGLO1KDM4ELMNA | |
| SCHEMBL26964376 | 0.78 | SLC40A1 (0.43) | ALDH1A1GAAGLO1KDM4ELMNA | |
| SCHEMBL22315304 | 0.76 | PTGES2 (0.44) | ALDH1A1MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| EP-0991624-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000371-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-01-07 | — | — | WO | disclosed |