Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983343 | 0.88 | DRD2 (0.46) | ALDH1A1POLBTSHRHPGD | |
| SCHEMBL6978716 | 0.87 | MEN1 (0.48) | ALDH1A1KDM4ESMN1; SMN2KMT2ALMNA | |
| SCHEMBL6984699 | 0.86 | ALDH1A1 (0.40) | ALDH1A1POLBKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL6981792 | 0.85 | POLB (0.47) | ALDH1A1POLBCYP2C19KDM4ESMN1; SMN2 | |
| SCHEMBL8579633 | 0.83 | DRD3 (0.40) | ALDH1A1SMN1; SMN2KMT2AGAALMNA | |
| SCHEMBL6976774 | 0.82 | CA12 (0.44) | ALDH1A1POLBKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL6980780 | 0.73 | CACNA2D1 (0.43) | GAATSHRTDP1HPGD | |
| Hydrochloric Acid SCHEMBL6984558 | 0.72 | SIGMAR1 (0.43) | ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL6974100 | 0.72 | NPC1 (0.48) | ALDH1A1POLBCYP2C19KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL6983896 | 0.72 | SIGMAR1 (0.48) | ALDH1A1KDM4EKMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-B1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-6172085-B1 | CENTRAL NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |