Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 5/20 | 0.69 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10187442 | 0.95 | PYCR1 (0.69) | PYCR1HRH3KDM4EALDH1A1HDAC8 | |
| SCHEMBL7768079 | 0.87 | HRH3 (0.84) | PYCR1HRH3HDAC8HDAC6 | |
| SCHEMBL27863482 | 0.87 | PYCR1 (0.61) | PYCR1HRH3KDM4EALDH1A1HDAC8 | |
| SCHEMBL4592107 | 0.84 | ALDH1A1 (0.59) | PYCR1HRH3KDM4EALDH1A1HDAC8 | |
| SCHEMBL2253179 | 0.83 | HRH3 (0.70) | PYCR1HRH3KDM4EALDH1A1HDAC8 | |
| SCHEMBL22340499 | 0.82 | PYCR1 (0.64) | PYCR1HRH3KDM4EALDH1A1HDAC8 | |
| SCHEMBL4592097 | 0.81 | PYCR1 (0.54) | PYCR1HRH3KDM4EALDH1A1HDAC8 | |
| SCHEMBL3620117 | 0.81 | KDM4E (0.56) | PYCR1HRH3KDM4EALDH1A1HDAC8 | |
| SCHEMBL5926009 | 0.80 | HRH3 (0.73) | PYCR1HRH3HDAC8HDAC6 | |
| SCHEMBL12680476 | 0.80 | HRH3 (1.00) | PYCR1HRH3HDAC8HDAC6TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017112576-A1 | METHODS FOR EXTERNAL BASE-FREE SUZUKI COUPLINGS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-06-29 | — | — | WO | disclosed |
| US-9682970-B2 | Fluorescent compounds and uses thereof | BIOTIUM, INC. (US) | 2017-06-20 | — | — | US | disclosed |
| EP-1885718-B1 | FLUORESCENT CHEMICAL COMPOUNDS HAVING HIGH SELECTIVITY FOR DOUBLE STRANDED DNA, AND METHODS FOR THEIR USE | LIFE TECHNOLOGIES CORP (US) | 2017-03-15 | — | — | EP | disclosed |
| US-9453025-B2 | Tricyclic compounds and PBK inhibitors containing the same | ONCOTHERAPY SCIENCE, INC. (JP) | 2016-09-27 | — | — | US | disclosed |
| US-9382425-B2 | Aza-benzazolium containing cyanine dyes | Life Technologies Corporation (US) | 2016-07-05 | — | — | US | disclosed |
| US-9366676-B2 | Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use | Life Technologies Corporation (US) | 2016-06-14 | — | — | US | disclosed |
| US-9279806-B2 | Water-soluble AIE luminogens for monitoring and retardation of fibrillation of amyloid proteins | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-03-08 | — | — | US | disclosed |
| US-9279806-B2 | Water-soluble AIE luminogens for monitoring and retardation of fibrillation of amyloid proteins | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-03-08 | — | — | US | disclosed |
| US-9279806-B2 | Water-soluble AIE luminogens for monitoring and retardation of fibrillation of amyloid proteins | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-03-08 | — | — | US | disclosed |
| US-20160024067-A1 | FLUORESCENT COMPOUNDS AND USES THEREOF | BIOTIUM, INC. | 2016-01-28 | — | — | US | disclosed |
| US-20080044811-A1 | nucleic acid or a poly(amino acid) samples and dyes in form of staining solution are combined for sufficient time to form dye-analyte complex and are illuminated with an appropriate wavelength whereby nucleic acid or a poly(amino acid) is detected | INVITROGEN CORPORATION (US) | 2008-02-21 | — | — | US | disclosed |
| EP-1885718-A1 | FLUORESCENT CHEMICAL COMPOUNDS HAVING HIGH SELECTIVITY FOR DOUBLE STRANDED DNA, AND METHODS FOR THEIR USE | Molecular Probes, Inc. (US) | 2008-02-13 | — | — | EP | disclosed |
| US-7226740-B2 | nucleic acid or a poly(amino acid) samples and dyes in form of staining solution are combined for sufficient time to form dye-analyte complex and are illuminated with an appropriate wavelength whereby nucleic acid or a poly(amino acid) is detected | INVITROGEN CORPORATION (US) | 2007-06-05 | — | — | US | disclosed |
| US-20070111981-A1 | New (hetero)aryl compounds with MCH antagonistic activity and medicaments comprising these compounds | ROTH GERALD J | 2007-05-17 | — | — | US | disclosed |
| WO-2007048802-A1 | (HETERO)ARYL COMPOUNDS WITH MCH ANTAGONISTIC ACTIVITY AND MEDICAMENTS COMPRISING THESE COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-05-03 | — | — | WO | disclosed |
| WO-2006124816-A1 | FLUORESCENT CHEMICAL COMPOUNDS HAVING HIGH SELECTIVITY FOR DOUBLE STRANDED DNA, AND METHODS FOR THEIR USE | MOLECULAR PROBES, INC. (US) | 2006-11-23 | — | — | WO | disclosed |
| US-20060263844-A1 | Flourescent chemical compounds having high selectivity for double standard DNA, and methods for their use | MOLECULAR PROBES, INC. | 2006-11-23 | — | — | US | disclosed |
| US-20040137475-A1 | nucleic acid or a poly(amino acid) samples and dyes in form of staining solution are combined for sufficient time to form dye-analyte complex and are illuminated with an appropriate wavelength whereby nucleic acid or a poly(amino acid) is detected | Life Technologies Corporation | 2004-07-15 | — | — | US | disclosed |
| US-6664047-B1 | Assymetrical; substituted by a cationic side chain; exhibit bright fluorescence when associated with nucleic acid polymers such as DNA or RNA, or with polypeptides | MOLECULAR PROBES, INC. | 2003-12-16 | — | — | US | disclosed |
| WO-2000066664-A1 | AZA-BENZAZOLIUM CONTAINING CYANINE DYES | MOLECULAR PROBES, INC. (US) | 2000-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070111981-A1 | New (hetero)aryl compounds with MCH antagonistic activity and medicaments comprising these compounds | MCHR1, GPR119, MCHR2 | PYCR1 387/4885HRH3 89/4885KDM4E 1313/4885 |
| US-20040137475-A1 | nucleic acid or a poly(amino acid) samples and dyes in form of staining solution are combined for sufficient time to form dye-analyte complex and are illuminated with an appropriate wavelength whereby nucleic acid or a poly(amino acid) is detected | POLL, IK, ADAR | PYCR1 493/4885HRH3 3109/4885KDM4E 1578/4885 |
| US-20160024067-A1 | FLUORESCENT COMPOUNDS AND USES THEREOF | POLI, POLL, POLRMT | PYCR1 1429/4885HRH3 1659/4885KDM4E 4469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.